Many folk enjoy the health benefits of grapefruit alternatively grapefruit drink as part of their yearly breakfast routine. These citrus fruits cater a natural source of vitamin C and fiber. However,http://www.nanobio.com,folk who are taking prescription medications need to be aware of the feasibility of an interaction between their medicine and grapefruit. This interaction was identified within the late 1980s. Some patients were initially advised just to separate the potion of medication from the grapefruit juice merely it namely now known that grapefruit alternatively grapefruit juice cannot be consumed at always while taking certain prescriptions.
How Grapefruit Juice Affects Drugs
Most medications enter the body through the jaws and are broken down by enzymes amid the intestines and the liver. Natural chemicals among grapefruit block the movement of an of these enzymes,kate spade handbags, known as CYP3A4. This enzyme helps to crash down several commonly acclimate medications. When the chemicals among grapefruit drink blocks the enzyme,ray ban aviator, this can adviser to changes amid blood levels of the medicine. In some cases,kate spade outlet, levels of the medication ambition become also lofty and occasionally,kate spade coupon,too low.
Prescription Medications Affected by Grapefruit
Not all medications interact with grapefruit,http://www.m-goldberg.com. Most prescriptions and over-the-counter medications ambition never be affected,kate spade bags. Some commonly accustom medications that patients do need to watch with grapefruit beverage include:
amiodarone (Cordarone,ray ban new wayfarer, Pacerone) for heartsimvastatin (Zocor) and lovastatin (Mevacor,ray ban sunglasses sale,ruddy yeast rice) for cholesterolnifedipine (Adalat, Procardia) and verapamil (Calan) for blood pressuretacrolimus (Prograf) for immunosuppressiontriazolam (Halcion) and midazolam (Versed) as twilight nap ahead a procedureerythromycin as infection and gastroparesis
According to Pharmacy Times, some of these interactions can be dangerous. Nilotinib (Tasigna) is an oral medication used to treat leukemia. The prescribing information as nilotinib notes that grapefruit juice can block collapse of this medication which could guide to a fatal heart arrhythmia known as long QT syndrome. Erythromycin is used as an antibiotic and to multiplication digestion of edible amid gastroparesis. Combining grapefruit with erythromycin can also adviser to a heart arryhthmia.
Further Information aboard Grapefruit Juice and Medications
The Florida Department of Citrus has published a handy plan for patients to use to detain their medications and the severity of the potential interaction. Anyone with questions aboard consuming grapefruit with their specific prescriptions should contact their pharmacist alternatively prescriber. Alternative medications may be accessible to use instead.
Sources:
Read aboard
What to Drink with Medication
Gorgeous Grapefruit
How Fruit Juice Affects Medication Blood Levels
Shimomura, S. Drug Interactions with Grapefruit Juice: An Evidence-Based Overview. Pharmacy Times. 2006. Accessed March 30, 2010.
Grapefruit Interactions Quick Check. The Florida Department of Citrus. 2010. Accessed March 30, 2010.
Grapefruit-Drug Interaction Information for Patients. Center for Drug Interaction Research and Education. druginteractioncenter.org. Accessed March 30, 2010.
Tasigna Important Safety Information. Accessed March 30, 2010.
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